Reflections & analysis about innovation, technology, startups, investing, healthcare, and more .... with a focus on Minnesota, Land of 10,000 Lakes. Blogging continuously since 2005.

Category: Startups (Page 5 of 29)

What’s the Future for MedTech Startups? Reasons to Be Worried (and a Ray of Hope)

[NOTE: This post first appeared at Minnov8.com. My friends at Rochester Rising in southern MN also ran a version of it later.]

Living and working here in Minnesota, as I do, you constantly hear about how wonderful our state’s medical technology industry is. After all, we’re the No. 1 Global Medtech Cluster, as I was reminded again here at the AdvaMed 2016 conference.  We all think we’re sitting on this huge industry that will just keep growing forever and bring bountiful riches to our state. Well, it turns out things are not all that rosy.futureatrisk-cover280w

I learned today about a new report, “A Future at Risk: Economic Performance, Entrepreneurship, and Venture Capital in the U.S. Medical Technology Sector.”

Here’s the gist:

“The American medical technology industry has been suffering from a steady decline of entrepreneurship for more than two decades…”

What? Yes, it’s a fact: the numbers associated with this engine of innovation (and jobs) have been declining quite markedly.

We can relate to the medtech startup engine very well here in Minnesota, with our own giant Medtronic having been started by Earl Bakken in a garage in Northeast Minneapolis. (I worked for the company early in my career and got to be taken out for a welcome lunch by the man himself.)

Two charts from the report, shown here, will surprise many. (Click for larger view.) startupdensity-chart-kauffman

newcoformations-chartHere’s more from the report’s executive summary:

“The (medtech) industry is increasingly concentrated in a shrinking number of large players. All of those companies are scouring the globe for medtech innovation. With fewer startups in the system, the industry’s dominant companies recognize the long-term threat to innovation represented by fewer companies fueling the industry’s pipeline of innovation. All these factors represent a present and future threat to American leadership in the industry, to medical innovation and, ultimately, to patients.” Continue reading

TreeHouse Health Names Its 13th Portfolio Company

The winner of the 2016 Minnesota Cup, the largest business plan competition in the U.S., has been named by healthcare-startup incubator TreeHouse Health in Minneapolis as its latest portfolio company. StemoniX is leading the development and manufacturing of human-induced pluripotent stem cells for pharmaceutical drug-discovery applications, such as biologically accurate, miniaturized organ-like microtissues.TreeHouse-FinalLogo

“We are excited to announce the addition of StemoniX to the TreeHouse Health ecosystem,” said J.D. Blank, managing director, in a prepared statement. “Through their innovative work, they are advancing the field of drug discovery and ultimately helping patients get better treatment more quickly.”

StemoniX’s biotechnology provides scientists with standardized, easy-to-use, cost-effective access to relevant human microtissue for toxicity and efficacy screening. stemonix-logoIncorporated in Minnesota, the company is colocated in Minneapolis and San Diego, California.

TreeHouse Health defines itself as an “innovation center” designed to invest in emerging healthcare companies and help accelerate their growth. It says Stemonix is setting a new standard for stem cell technologies to meet the demands of drug discovery and personalized medicine.

mncup-logo-squareStemoniX earned the Grand Prize and title of “Best Breakthrough Business Idea of 2016” at the 12th annual MN Cup awards, held on September 22, 2016 at the University of Minnesota.

StemoniX says its efforts are revolutionizing stem cell-based research and drug screening and will lead to a new era of drug discovery and personalized medicine. “We’re grateful to become part of TreeHouse Health as a portfolio company,” said Ping Yeh, CEO. “We’re confident our relationship with TreeHouse Health will help us establish a strong presence in Minnesota, as well as generate new opportunities for Minnesota-based financing and collaborative partnerships with TreeHouse Health anchor tenants and other connections.”

TreeHouse Health now has 13 portfolio companies.

TreeHouse Health now has 13 portfolio companies.

Yeh continued: “We are thankful to the MN Cup organizers, sponsors, and community for their support and the opportunities created by our participation in the competition this year, which includes our new relationship with TreeHouse Health.”

Along with providing investment, TreeHouse Health offers its portfolio companies access to its ecosystem consisting of leading healthcare organizations (its “anchor tenants”), professional service providers, and other emerging healthcare companies. To date, TreeHouse Health has invested in thirteen early-stage healthcare companies and has anchor tenant relationships with Hennepin County Medical Center (HCMC), Blue Cross and Blue Shield of Minnesota (BCBS), and Accenture.

 

My Live Blog of the 2016 ‘Pioneer Summit’…

pioneersummit-ggbridgeskyline

I just wrapped up my live blogging at the Pioneer Summit in Redwood City, CA, covering both days of the conference, September 14 and 15, 2016. More than 1,500 attended. Here’s how the organizers described the conference:

“The agenda is packed with thrilling conversations on the ideas and people who will shape the world. Whether you’re inspired by game-changing entrepreneurs building our robotic future, or determined investors that fuel billion-dollar startups, the Pioneer Summit is bringing the Global Silicon Valley’s best and brightest to Redwood City.”

They weren’t kidding — it was packed with awesomeness!

What follows is my complete live blog, now archived in chronological order.

(Also see a selection of the photos I took at the event in this Flickr Album.)

———–

NOTE: Unfortunately, updates to WordPress software since I originally published this post caused the Live Blog plugin to break. I got no warning. Nice going, WordPress! So, my content appears to be lost forever… 🙁  

I guess you just had to be there! Trust me, it was good.

My Latest Post on LinkedIn Is About ‘Bootstrapping’

(Note: I posted the following on my LinkedIn page earlier today and decided to repeat it here. It was entitled, “Bootstrapping: Why Do Entrepreneurs Do It, and How?”)

Photo: @LLBean

Photo: @LLBean

The word “bootstrapping” actually has several meanings according to Wikipedia. But in a business context, it means “to start a business without external help (capital).” You can read more about that specific meaning, also called “bootstrap funding,” here on Wikipedia — lots of helpful information there. Okay, now that I’m sure you know what it means…

What got me thinking about bootstrapping recently was tripping on an old blog post of mine, which is still very timely in our current startup climate. It was called “Raising Startup Money? Here’s 20 Ways.” Note the “Big List” included in that post, called “20 Way$$ to Feed Your Startup Habit.” A large number of those 20 ways fit into the spirit of bootstrapping. Yes, the money you save as a bootstrapping entrepreneur is as good as any other money — maybe better.

Before I wrote that piece above, I got inspired about bootstrapping by a blog post written by a guy named Jeff Cornwall. He heads the entrepreneurial studies program at Belmont University (and used to teach here in the Twin Cities at the University of St. Thomas). That blog post was entitled “Why Do We Bootstrap?” The interesting thing Dr. Cornwall said he’d found in his work was that entrepreneurs bootstrap for a wide variety of reasons, and only some of them relate to necessity. Some just do it because they like it, I guess — and to allow them to keep more ownership of their company, which is no small benefit. (Jeff’s web site is here, and he also runs a well-followed community site called The Entrepreneurial Mind.)

The other reason I find the topic of bootstrapping interesting is that I’ve practiced it myself and worked with many founders who’ve done the same over my 30+ year career working with tech startups. In addition, I think there’s especially a need here in the Midwest for founders to get more educated on this topic. Why? Because, try as we might, startup venture funding is never going to flow as freely here as it does in Silicon Valley, or Boston, or Austin, or you name it.

Entrepreneurs in these parts, and in so many areas of the country away from the major VC hubs, have to be one thing above all else: clever. And there’s a lot they can learn from people who study this phenomenon, and people who’ve practiced it for a long time. We have tons of those here in Minnesota (and all over, really) — serial entrepreneurs who’ve proved bootstrapping works. Many of these folks are friends of mine, and they’ve accumulated a large amount of knowledge on bootstrapping based on hard experience. The key, of course, if you’re a budding entrepreneur, is to learn how to tap into the expertise of those folks — find them and learn from them. (Think mentors.)

Let me also suggest a couple of great, short books on bootstrapping. Dr. Jeff Cornwall, mentioned above, published one in 2009 simply called Bootstrapping. Way before he published that book, he recommended one by Seth Godin, called the “Bootstrapper’s Bible.” It’s certainly not a new book, but no matter — it’s a timeless classic. (Here’s some background on it from Seth’s blog.

The price is right.

The price is right.

But, wait — here’s a big tip for you: don’t buy it. That’s right, save your money! Because you can download an ebook version of it that Seth published for free. He calls his ebook a “manifesto” and you can get it as as a PDF file right here.

How’s that for a bootstrapping move! Go grab it while you can, before Seth changes his mind. Then, read up, go forth, and continue bootstrapping your way to startup success. Ka-ching!

 

 

DoApp Has Been Acquired by Newscycle Solutions

DoApp logoDoApp has gone and done it — and, yes, it’s cool.

The highly successful Minnesota mobile startup has been acquired by Newscycle Solutions, a 500-employee Bloomington MN-based firm that “develops and delivers software technology to empower the global news media industry.” DoApp has developed more than 1,500 mobile apps for the news publishing and broadcast industries.  All DoApp employees will join Newscycle. The acquisition closed on June 10, 2016; the price was not announced.

DoApp was founded in early 2008 by former Google employee Joe Sriver and a small team. It has been entirely self-funded and profitable for six years. Newscycle Solutions is made up four merged companies and is owned by Vista Equity Partners, based in San Francisco, which was the most active firm in the M&A business last year. (Within the past two weeks alone, it acquired Marketo and Ping Identity, deals valued collectively at $2.4 billion.) Continue reading

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